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Finally, several small molecules with moderate activity were obtained in the screening, including several derivatives of naphtoquinones, which are also inhibitors of the NF-B pathway (Supplementary Table 4)

(PubMed) Weng HX, Liu HP, Li DW, Ye M, Pan L, Xia TH

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This means that EpCAM-specific antibodies are conjugated with cytotoxic agents, such as doxorubicin, paclitaxel, calicheamicin, topoisomerase I inhibitors, alpha amanitin, and indolinobenzodiazepine pseudodimers (IGNs), to specifically kill the EpCAM+ tumor cells